Formulation and Evaluation of Immediate Release Tablet Dosage Form of Linagliptin and Metformin Hydrochloride
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چکیده
منابع مشابه
Formulation and Development of Floating Drug Delivery System of Metformin Hydrochloride Extended Release and Glimepiride Immediate Release into Bilayered Tablet Dosage Form: in Vitro Evaluation
The purpose of the research work was formulation development and evaluation bi-layer floating tablets for metformin hydrochloride and glimepiride to improve the oral therapeutic efficacy Both these drugs exhibit pH dependent solubility and show good permeability from stomach and upper part of the small intestine into systemic circulation. Direct compression method form metformin hydrochloride l...
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An attempt was made to sustain the release of metformin HCl as well as to mask the bitter taste by complexation technique using strong cation-exchange resins, indion 244 and indion 264. The drug loading onto ion-exchange resin was optimized for mixing time, activation, effect of pH, mode of mixing, ratio of drug:resin and temperature. The resinate was evaluated for micromeritic properties, tast...
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sustained release oral delivery systems are designed to achieve therapeutically effective concentrations of drug in the systemic circulation over an extended period of time. the purpose of the present investigation was to design and evaluate sustained release matrix tablets of nifedipine, a poorly water soluble drug, employing hydroxypropyl methyl cellulose ( hpmc) and ethyl cellulose ( ec) as ...
متن کاملSimultaneous Estimation of Metformin Hydrochloride and Pioglitazone Hydrochloride by RPHPLC Method from Combined Tablet Dosage Form
A high performance reverse phase liquid chromatographic procedure is developed for simultaneous estimation of metformin hydrochloride and pioglitazone hydrochloride in combined tablet dosage form. The mobile phase used was a combination of acetonitrile:water:acetic acid (60:40:0.3) and the pH was adjusted to 5.5 by adding triethylamine. The detection of the combined dosage form was carried out ...
متن کاملFormulation and Evaluation of Immediate Release Tablet of Telmisartan
Introduction Medications are only one part of a successful treatment plan. They are appropriate when they provide benefit, improve function and have either no or mild, manageable side effects. Importantly, medications (even if natural) are chemical substances not expected in the body, and as such have side effects. Some of the side effects might be unknown. The use of medications or drugs for a...
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ژورنال
عنوان ژورنال: Journal of Drug Delivery and Therapeutics
سال: 2021
ISSN: 2250-1177
DOI: 10.22270/jddt.v11i3-s.4831